What are monoclonal antibodies?

Monoclonal antibody treatments are laboratory-made proteins that work in your body by attaching to parts of the virus and helping your immune system respond more quickly to fight it. The U.S. Food and Drug Administration has issued Emergency Use Authorizations (EUA) for two monoclonal antibody treatments for COVID-19 for people at high risk of getting very sick. Casirivimab/imdevimab (REGEN-COV®) by Regeneron is a monoclonal antibody that is authorized for the treatment of mild-to-moderate COVID-19 in non-hospitalized adult and pediatric patients. Early studies suggest some people may benefit from monoclonal antibody treatment soon after they’re infected with COVID-19 and may have a lower risk of hospitalization.

If you test positive for COVID-19 and meet the following criteria, you may be eligible to receive a monoclonal antibodies infusion:

  • Your COVID-19 test comes back positive
  • You are not hospitalized
  • You have had mild to moderate symptoms that started less than 10 days ago
  • You have certain medical conditions or other factors that may place adults and pediatric patients (age 12-17 years, and weight at least 88 lbs.) at higher risk of progressing to severe infection:
    • Age 65 years or older
    • Obese or overweight which may include a Body Mass Index (BMI) of 25 or higher for adults or a BMI in the 85th percentile or higher on the growth chart for pediatric patients
    • Pregnant
    • Diabetes
    • Chronic kidney disease
    • Immunosuppressive disease, or on immunosuppressive treatment
    • Cardiovascular disease (including congenital heart disease) or hypertension
    • Chronic lung disease such as chronic obstructive pulmonary disease (COPD),moderate to severe asthma, cystic fibrosis, or pulmonary hypertension)
    • Sickle cell disease

Why would I consider receiving a monoclonal antibodies infusion?

An infusion / injection may minimize the potential for higher risk patients to progress to severe disease and/or hospitalization

If you believe that you would be an appropriate candidate for these therapies, then please contact your medical provider to see if an infusion / injection is right for you.

If you do not have a medical provider, view available treatment sites to find the nearest place that may be able to discuss this option and may treat you. 

Monoclonal antibodies should not be considered the standard of care for the treatment of all patients with COVID-19.

For frequently asked questions on monoclonal antibodies infusion, please see Monoclonal Antibody Treatment FAQs